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enhances brain serotonin, useful for anxiety, insomnia, stress, etc.
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Enhances brain serotonin
*5-Hydroxytryptophan (5-HTP) is an intermediate in the natural
synthesis of the essential amino acid, tryptophan, to serotonin.
In clinical studies, administration of 5-HTP increased serotonin levels.
The enzyme tryptophan hydroxylase adds a hydroxyl group (OH) to
tryptophan, forming the 5-HTP intermediate. In the body, it converts
to serotonin with the removal of a carboxyl group (COOH) by a
second enzyme. The 5-HTP supplied in supplement is derived from
the Griffonia simplicifolia plant. Serotonin is an important
neurotransmitter involved in the regulation of endocrine and brain
activity responsible for emotion, appetite and wake/sleep/wake cycles.
Supplementation with 5-HTP encourages brain serotonin levels that
can lead to positive effects on emotional well-being, appetite control,
and sleep/wake/sleep cycles.
Reference: Cangiano C, Laviano A, Del Ben M, Preziosa I, Angelico F, Cascino
A, Rossi-Fanelli F. Effects of oral 5-hydroxy-tryptophan on energy intake and
macronutrient selection in non-insulin dependent diabetic patients. Int J Obes
Relat Metab Disord 1998 Jul;22(7):648-54.